Davit T․ Babikyan

My consultations
Geneticist
Speciality

Qualification of European Clinical Laboratory Geneticist

Associate Professor, Department of Medical Genetics, Yerevan State Medical University after Mkhitar Heratsi

Head of the Laboratory of Molecular Genetics, Center of Medical Genetics and Primary Health Care

Position
34/3 Abovyan st., Yerevan, 0001, Armenia
Address
+374 10 544 367
Phone
Question to doctor

Scientific Degree

PhD of biology

Rank

Associate professor

Education

1995-1999
Biophysics, Faculty of Biology, Yerevan State University, Bachelor's Degree
1999-2001
Genetics and Cytology, Faculty of Biology, Yerevan State University, Master's Degree
2001-2004
Genetics, Center for Medical Genetics, NAS RA, PhD

Trainings

2018
"Provision of Quality of Diagnosis of Molecular Genetic Diseases", Kaiser Permanent, California, USA
2018
"Pre-implantation genetic diagnosis and screening", Belinson Medical Center, Tel Aviv, Israel
2017
"Medical Education Quality Assurance", Graz Medical University, Graz, Austria
2017
Qualification of European Clinical Laboratory Geneticist, Professional Commission of European Clinical Genetics
2017
"NGS Diagnosis", Tel Aviv University, Belinson Medical Center, Tel Aviv, Israel
2016
"Genetic Platforms for Diagnosis of Hereditary Diseases", Imagine Institute, Hopital Neker, Paris, France
2015
"NGS and Bioinformatics", Welcome Trust Center, Cambridge, UK "Clinical genetics and genetic counseling", University of Plymouth, UK
2015
"Medical Genetics", Graz Medical University, Graz, Austria
2015
"Cancer Genetic Counseling, Exome Sequencing and Bioinformatics", Bologna University, Bologna, Italy
2013
NGS for genetic diagnosis, University of Copenhagen, Denmark
2012
"Genetic Background of the Intellectual Disability", Bologna University, Bologna, Italy
2011
"Molecular Genetic Diagnosis", Hopital Henri Mondor, Paris, France
2011
"Molecular Basis of Autoinflammatory Diseases", Hopital Armand Trousseau, Paris, France
2011
"Genetic Background of the Intellectual Disability", Bologna University, Bologna, Italy
2010
"Molecular Genetic Diagnosis", Hopital Henri Mondor, Paris, France
2010
"Molecular Basis of Autoinflammatory Diseases", Hopital Armand Trousseau, Paris, France
2010
"Discovery of Genomic Changes", Tartu University, Estonia
2010
"Genetic Background of the Intellectual Disability", Karloff University, Prague, Czech Republic

Professional activity

Since 2011
Associate Professor, Department of Medical Genetics, Yerevan State Medical University after Mkhitar Heratsi
Since 2007
Head of the Laboratory of Molecular Genetics, Center of Medical Genetics and Primary Health Care
2005-2007
PhD researcher, International Center for Cancer Research, Lyon, France
2004-2005
Researcher, Medical Genetics Center of NAS RA, Yerevan, Armenia
2001-2003
Junior Researcher, Institute of Molecular Medicine, Huntington Beach, California, USA

Publications

2017
Moradian MM, Babikyan D, Banoian D, Hayrapetyan H, Manvelyan H, Avanesian N, Sarkisian T. Comprehensive analysis of mutations in the MEFV gene reveal that the location and not the substitution type determines symptom severity in FMF. Mol Genet Genomic Med. 2017 Nov;5(6):742-750
2017
Բաբիկյան Դ. Քաղցկեղի կլինիկական գենետիկա. Ուսումնամեթոդական ձեռնարկ. ԵՊԲՀ. 2017
2016
Babikyan D. The Utility of Sufficiently Informative Protein Multiple Sequence Alignment For Cancer Risk Assessment of BRCA2 Missense Substitutions. Biological Journal of Armenia, 4(68) 76-80, 2016
Babikyan D. High-Resolution Melt Curve Analysis as a High-Throughput screening method of large genes (տպագրության մեջ)
2016
Babikyan D, Zakharyan A. Role of genetic diagnosis for patients with suspicion of thalassemia intermediate/minor. EHA Learning Center. Jun 9, 2016; 135019
2015
Melik-Pashayan, Andryushenko, Babikyan, Mironova, Aghekyan. Genetic markers of depression recurrence in Russian and Armenian population. The New Armenian Medical Journal, Yerevan 2015. 9 (3): 107
2015
Бабикян Д.Т. Глава. Генетика мужского бесплодия. 388-409. Книга. Мужское Здоровье. Мурадян А.А. Ереван 2015
2014
D. Babikyan, S. Midyan, A. Hovhannisyan, A. Gasparyan, T. Sarkisian. De novo single exon deletion of AUTS2 in a patient with profound intellectual disability. Eur. J Hum. Genet. 2014 May 22:151
2013
Դ.Թ. Բաբիկյան, Ս.Ա. Միդյան, Ա.Հ. Հովհաննիսյան, Հ.Ս. Մկրտչյան, Ա.Վ. Գասպարյան, Ջ. Հեթինգեր, Ա.Կուրգ, Ֆ. Պատսալիս, Թ.Ֆ. Սարգսյան 1q21.3 քրոմսոսմային հատվածի միկրոդուպլիկացիան որպես մտավոր հետամնացության նոր գենետիկական պատճառ. ԵՊԲՀ հաշվետու տարեկան գիտաժողով-2013: Գիտական հոդվածների ժողովածու, Երևան 2013, Հատոր1. 251-257
2013
D Babikyan, I Jeru, B Copin, H Hayrapetyan, S Amselem, T Sarkisian. FMF-like state: genetic factors unrelated to MEFV. Pediatric Rheumatology 2013, 11(Suppl 1):A85:29-30
2012
D. T. Babikyan, H. Mkrtchyan, S. Midyan, M. Nõukas, K. Männik, A. Hovhannesyan, A. Gasparyan1, T. Liehr, A. Kurg, T. F. Sarkisian; Molecular cytogenetic characterization of a family with 3p deletion and 3p duplication cases Eur. J Hum. Genet. 2012 May 20:52
2012
C. Graziano, E. Bonora, J. A. Hettinger, K. Männik, P. Magini, M. Badura-Stronka, E. Õiglane-Slik, J. Kasnauskienè, I. Lebedev, M. Havlovicova, D. Babikyan, L. A. Livshits, T. Sarkisian, A. Latos-Bieleńska, V. Kučinskas, Z. Sedlacek, P. C. Patsalis, A. Kurg, G. Romeo1. CHERISH - Improving Diagnoses of Mental Retardation in Children in Eastern Europe and Central Asia through Genetic Characterisation and Bioinformatics/Statistics - a GENOMIC PROJECT. Eur. J Hum. Genet. 2012 May 20:272-273
2012
Vallée MP, Francy TC, Judkins MK, Babikyan D, Lesueur F, Gammon A, Goldgar DE, Couch FJ, Tavtigian SV Classification of Missense Substitutions in the BRCA Genes: a Database Dedicated to Ex-UVs. Hum Mutat. 2012 Jan;33(1):22-8
2011
D. Babikyan, S. Midyan, K. Mannik, S. Parkel, A. Hovhannisyan, H. Mkrtchyan, A. Gasparyan, A. Kurg, T. Sarkisian. Use of SNP-array in a cohort of Armenian children with mental retardation. Eur. J Hum. Genet. 2011 May 19:136
2011
A. Kurg, K. Männik, M. Nõukas, O. Zilina, E. Õiglane-Šlik1, C. Graziano, E. Bonora, P. Magini, J. Baptista, G. Tortora, S. Miccoli, P. C. Patsalis, J. A. Hettinger, V. Anastasiadou, V. Kučinskas, J. Kasnauskienè E. Preikšaitienė, I. Lebedev, A. Latos-Bieleńska, M. Badura-Stronka, S. Debicki, Z. Sedlacek, M. Havlovicova, M. Vlckova, M. Hancarova, T. Sarkisian, D. Babikyan, S. Midyan, L. A. Livshits, G. Romeo. CHERISH - Improving Diagnoses of Mental Retardation in Children in Eastern Europe and Central Asia through Genetic Characterisation and Bioinformatics/Statistics. 15th International Workshop on Fragile X and Early-Onset Cognitive Diseases, Berlin, Germany, September 4-7 2011
2011
H. Puehringer, B. Rauscher, T.Sarkisian, K.Pagava, H.Hayrapetyan, D.Babikyan, I.Korinteli, M.Korinteli, C.Oberkanins. Thalassemia carrier screening in the transcaucasian countries Armenia and Georgia. 12th International Conference on Thalassaemia and other Haemoglobinopathies. May 2011, Abstract book, 55
2011
Le Calvez-Kelm F, Lesueur F, Damiola F, Vallee M, Voegele C, Babikyan D, Durand G, Forey N, McKay-Chopin S, Robinot N, Nguyen-Dumont T, Thomas A, Byrnes GB, Breast Cancer Family Registry T, Hopper JL, Southey MC, Andrulis IL, John EM, Tavtigian SV. Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry (CFR) case-control mutation screening study. Breast Cancer Res. 2011 Jan 18;13(1):R6
2010
C. Graziano, E. Bonora, P. Magini, J. Baptista, G. Tortora, S. Miccoli, K. Mannik, T. Sarkisian, D. Babikyan, S. Midyan, G. Romeo, etc. CHERISH- Improving Diagnoses of Mental Retardation in children in Eastern Europe and Central Asia through genetics characterization and Bioinformatics/Statistics. Eur. J. Hum. Genet. 2010 June 18:85
2010
D. Babikyan, H. Hayrapetyan, T.Davtyan, T. Sarkisian. Existence of FMF-like condition unrelated to MEFV. Eur. J. Hum. Genet. 2010 June 18:318
2009
Հակոբյան Ա., Սարգսյան Թ., Լյուլեջյան Կ., Միդյան Ս., Շահսուվարյան Գ., Բաբիկյան Դ. Մտավոր հետամնացության պատճառագիտությունը. Մարդու Առողջությունը VIII ազգային գիտաբժշկական կոնգրեսի նյութերի ժողովածու 2009: 288-289
2009
Tavtigian SV, Oefner PJ, Babikyan D, Hartmann A, Healey S, Le Calvez-Kelm F, Lesueur F, Byrnes GB, Chuang SC, Forey N, Feuchtinger C, Gioia L, Hall J, Hashibe M, Herte B, McKay-Chopin S, Thomas A, Vallée MP, Voegele C, Webb PM, Whiteman DC; Australian Cancer Study; Breast Cancer Family Registries (BCFR); Kathleen Cuningham Foundation Consortium for Research into Familial Aspects of Breast Cancer (kConFab), Sangrajrang S, Hopper JL, Southey MC, Andrulis IL, John EM, Chenevix-Trench G. Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer. Am J Hum Genet. 2009; 85(4):427-46
2009
Babikyan DT, Sarkisian TF. Preliminary genetic investigation of high-risk breast cacner patients in Armenia. European Journal of Human Genetics 2009; 17:S2:191
2008
Spurdle AB, Lakhani SR, Healey S, Parry S, Da Silva LM, Brinkworth R, Hopper JL, Brown MA, Babikyan D, Chenevix-Trench G, Tavtigian SV, Goldgar DE; kConFab Investigators. Clinical classification of BRCA1 and BRCA2 DNA sequence variants: the value of cytokeratin profiles and evolutionary analysis--a report from the kConFab Investigators. J Clin Oncol. 2008; 26(10):1657-63
2008
D.T.Babikyan, F. Lesueur, C. Voegele, M. Hashibe, J. Hall, G.B. Byrnes, S.V.Tavtigian. Analysis of ATM case-control mutation screening data. European Journal of Human Genetics, 2008, 16:sup2, p218-219
2008
D. Babikyan, F. Lesueur, C. Voegele, M. Vallee, F.Le Calvez-Kelm, M. Hashibe, C. Shu-Chun, J. Hall, G.B. Byrnes, S.V.Tavtigian. ATM in breast cancer susceptibility. European Journal of Cancer, 2008, 6:9, p11
2004
Babikyan D. Comparative analysis of anti-amyloid b immune responses generated after different routes of immunizations with plasmid encoding Ab-peptide immunogen fused with IL4 Медицинская наука Армении. 2004. т. XLIV, ¨1, с. 62-68
2003
Ghochikyan A, Vasilevko V, Petrushina I, Movsesyan N, Babikyan D, Tian W, Sadzikava N, Ross TM, Head E, Cribbs DH, Agadjanyan MG. Generation and characterization of the humoral immune response to DNA immunization with a chimeric beta-amyloid-interleukin-4 minigene Eur J Immunol. 2003 Dec; 33(12):3232-41
2003
Cribbs D.H., Lees A., Ghochikyan A., Vasilevko V., Petrushina I., Movsesyan N., Babikyan D., Tran M., DeVolger A., Agadjanyan M. Mannan as a Molecular Adjuvant for A-Immunotherapy. 6th International Conference on Progress in Alzheimer’s and Parkinson’s Diseases. New Trends in Alzheimer and Parkinson Related Disorders. Seville (Spain), 2003, p 81-85
2003
Cribbs D.H. Lees A., Ghochikyan A., Vasilevko V., Petrushina I., Movsesyan N., Babikyan D, Agadjanyan M.G. Th2 adjuvants and foreign T-cell epitopes for beta-amyloid immunotherapy. 33rd Annual Meeting of the Society for Neuroscience. New Orleans (USA), 2003
2003
Cribbs DH, Ghochikyan A, Vasilevko V, Tran M, Petrushina I, Sadzikava N, Babikyan D, Kesslak P, Kieber-Emmons T, Cotman CW, Agadjanyan MG. Adjuvant-dependent modulation of Th1 and Th2 responses to immunization with beta-amyloid. Int Immunol. 2003 Apr; 15(4):505-14
2001
Саркисян Т.Ф., Айрапетян А.С., Мнджоян Е.О., Оганесян З.Р., Бабикян Д.Т., Степанян Т.С. Перспективы ДНК-диагностики наследственной патологии на примере периодической болезни. Медицинская наука Армении. 2001, т. XLI, ¨ 2, с. 31-37
2001
Babikyan D., Grigoryan T., Sarkisian T. Phenotype-genotyp correlations in Armenian patients with FMF. In: “8th Armenian Medical World Congress.- Canada, 2001, p. 8-9
2001
Aйрапетян А.С., Мнджоян Е.О., Оганесян З.Р., Бегларян А.А., Степанян Т.С., Бабикян Д.Т., Григорян Т.С., САркисян Т.Ф.. Молекулярная диагностика периодической болезни среди армян. 2001, с. 11-15
2001
Sarkisian T., Ajrapetyan H., Mndjoyan E., Oganesyan Z, Babikyan D. Molecular study of MEFV gene mutations in Armenians Genetic Susceptibility at low Dose Exposure: 31st Annual Meeting of the European Environmental Mutagen Society.Ghent (Belgium), 2001, p. 90
2000
Բաբիկյան Դ. Գենոտիպի և ֆենոտիպի կորելացիաները պարբերական հիվանդների հայկական պոպուլյացիայում, Երիտ. գիտն. հոդվ. ժողով. Երևանի համալս. Հրատ., 2000, հ.2, էջ 84-87

Conferences

2017
"Laboratory Diagnosis of Medical Genetics", Conference of European Society of Human Genetics and European Clinical Laboratory Genetics Company, Athens, Greece
2017
ESHG 2017 Conference, Copenhagen, Denmark
2016
ESHG 2016 conference, Barcelona, Spain
2014
ESHG 2014 Conference, Milan, Italy
2013
ESHG 2013 Conference, Paris, France
2013
International Conference on Auto-inflammatory Diseases, Lausanne, Switzerland
2012
Meeting of European Association for Cancer Research (EACR21), Barcelona, Spain
2011
ESHG 2011 Conference, Amsterdam, The Netherlands
2010
International Conference on Auto-inflammatory Diseases, Amsterdam, The Netherlands
2010
ESHG 2010 Conference, Gofenberg, Sweden

Scientific works

PARTICIPATION IN INTERNATIONAL SCIENTIFIC PROGRAMS:
2015-2017
Project Manager of A2151 International Science and Technology Center (ISTC) Program "Nuclear and mitochondrial genetic variants and molecular bases of mitochondrial OXPHOS diseases"
2013-2017
Project Manager of EU Tempus MedGen Program "Developing Medical Genetics Education through Curriculum Reforms and Establishment of Postgraduate Training Programs"
2011-2013
Project Manager of EU FP7-INCO INARMERA Program “INTEGRATING ARMENIA INTO ERA”
2009-2012
Participant of EU FP7-HEALTH CHERISH Program “Improving Diagnoses of Mental Retardation in Children in Eastern Europe and Central Asia through Genetic Characterization and Bioinformatics/Statistics”
2008-2011
Project Manager of A1580 International Science and Technology Center (ISTC) Program “Molecular basis of the autoinflammation developed in FMF and related disorders”

Social activity

ORGANIZATION OF CONFERENCES:
2017
"National Medical Genetics Day" International Conference, Yerevan, Armenia
2015
"Autoinflammatory Disorder" International Conference, Yerevan, Armenia
2014
"MedGen: genetic health and genetic education" International Conference, Yerevan, Armenia
2010
“Modern Genetics in health Care system” International Conference, Yerevan, Armenia

Memberships

Member of European Society of Human Genetics (ESHG)
Member of Armenian Association of Human Genetics
Member of European Association for Cancer Research (EACR)

Question to doctor

Dear visitor, here you can contact with a doctor by e-mail. Please note that the site administration is not responsible for further communication or any information provided by your doctor.:

    Files should not exceed 2MB .

    The types of allowed files are png, gif, jpg, jpeg.